In order to use the route management you need

• Airline
• FBO at the airport of departure
• Terminal at the departure airport (always pay attention to the size)
• Business Lounge at the departure airport, if business taxis are to be generated
• FBO at destination airport
• Terminal at destination airport
• at least 1 aircraft in the airline

If you fly from the destination airport back to the departure airport and business paxes are to be generated there as well, a business lounge must also be rented there.